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Translational Medicine Friday

New Understandings Matter:  Neuro-Developmental DifferencES, Psychiatric Disorders, Shared Genes, Maternal Immune Activation & Blurred Categories of ADHD & AUTISM

10/7/2022

 

One of the big reasons we are in CRISIS MODE all the time for Mental Health is that the FOUNDATIONAL UNDERSTANDINGS are NOT SUFFICIENT.

That is starting to change --- BUT so many people are being missed because they don't fit into DSM CATEGORIES that are NOT TRUE FUNDAMENTAL CATEGORIES that track the UNDERLYING BIOLOGY.

BEING PRO SOCIALLY COMPETENT for the SOCIETY is GOOD --- BUT it is not really a SUBSTITUTE FOR UNDERSTANDING those underlying BIOMARKERS.

Conjecture

So One of the BIG New Understandings is that:
  • Psychiatric Disorders are often related to Neuro-Developmental Disorders.

The understanding above is very much related to the research that:
  • Psychiatric Disorders & Neuro-Developmental Differences/Disorders --- Share Common Genes.

These Neuro-Developmental Disorders are so BLURRED that many people are MISSED, and the research is bearing out that people with BLURRED aspects of ADHD and AUTISM are OFTEN MISSED.

Homeostasis / Sustainability may not be HUGELY DIFFERENT for Neuro-Diverse people (sometimes it is) --- BUT it is DIFFERENT ENOUGH that it matters.
  • People with Neuro-Developmental Differences / Disorders have RAMPED UP STRESS RESPONSES --
  • And often because they are OPERATING in TOTAL or SEMI-IGNORANCE -- they are subject to a lot of STRESS, and
  • They are more vulnerable to PSYCHIATRIC DISORDERS.
Kings College London (2019)
Thinking Twice About ADHD & Autism Spectrum Disorder

Emerging View that Anti-Social Personality Disorder is a Neuro-Developmental Disorder
Maternal Immune Activation Alters Adult Behavior
Picture
Neuroscience News
Brains of People With Schizophrenia Related Disorders Aren’t All the Same

https://neurosciencenews.com/schizophrenia-neurobiology-10430/
​

Canadian researchers say:

​
 "It turned out that the relationship between brain function and social behaviour had nothing to do with conventional diagnostic categories in the DSM-5 (Diagnostic and Statistical Manual of Mental Disorders).”

National Institute of Mental Health:  5 Disorders Share Common Genes (2013)
"Now that doesn't match with the idea that these are distinct."
See Also:

The Definitional Argument in Mental Health & Criminal Justice

NEXT FRIDAY:

More Conjecture

EPIGENETICS --- which can serve as a form of Neuro-Plasticity and Beyond.


Is it the BEST OF ALL POSSIBLE WORLDS, the WORST, IT DEPENDS?

IT is what it IS --- and we need to understand it a lot better than we do.

EPIGENETICS are more and more recognized as  critical mechanisms in auto-immune diseases, neuro-developmental differences, psychiatric disorders and cancer.


Comments are closed.

    Translational Medicine Friday

    We're riffing off NPR's Science Friday to create Translational Medicine Friday.

    We'll be collecting Research Article recommendations for Clinicians with regard to Cognitive Disability.

    ​There is much in the RESEARCH JOURNALS and we'll just be SKIMMING THE SURFACE.

    The POINT is to INCREASE FUNDING for TRANSLATIONAL RESEARCH at the Federal Level for the National Institutes of Health, the Centers for Disease Control, the Nation's Research & Teaching Hospitals and possible collaborations with Medicare and Medicaid providers.

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  • Home
    • About Orchid >
      • Why Orchid?
      • ORCHID'S SYSTEMIC FOCUS & "ROOT CAUSE" ANALYSIS APPROACH TO PROBLEM SOLVING WITH A COMMITMENT TO CREATIVITY & INNOVATION
      • Disclaimers, Limitations and An Invitation
      • Orchid Board
      • Orchid Book Club
      • Conjecture, Science & Translational Research & Medicine
      • Orchid Themes & Symbols
      • The Tipping Point
      • Orchid's Website Advertising Policy
      • Statement for Potential Website Contributors
      • Contact
  • Blogs
    • Val's Blog
    • Val's Blog 2
    • ​TRANSLATIONAL/ ​TRANSITIONAL JUSTICE MONDAY
    • NEURO-DIVERSITY Wednesday
    • Olmstead Law & Order Thursday
    • Translational Medicine Friday
    • Translational Love, Relationships & Neuro-Diversity Saturday
  • Orchid's A-Z Index
    • Crisis Services in CO, the US & Around the World
    • Assertive Community Treatment & Flexible ACT Index
    • Housing & Homelessness Index
    • Criminal Justice
    • Innovation Index
    • For More: See the Main Orchid Index Page
  • US Federal
    • THE IMD RULE & ADMIN. ENFORCEMENT OF DISABILITY CIVIL RIGHTS LAWS
    • Medicaid & Supportive Housing & Housing-Related Services
    • CMS' FAILURE TO COVER HOUSING FOR LTC & THE IMD RULE: WHAT THEY HAVE IN COMMON IS DISCRIMINATION
    • National Take
  • Research & Translational Medicine
    • Immunology & Mental Health >
      • Alcoholism & the Immune System & Mental Health
      • Brain Injury, the Immune System & Mental Health
      • Celiac Disease & Sensitivities, the Immune System & Mental Illness
      • Mental Illness & The Immune System
      • Racial Discrimination & the Immune System & Mental Health
      • Trauma & the Immune System & Mental Health
      • ***Physical Health Issues, the Immune System & Mental Health Index
    • University of Chicago: Institute of Translational Medicine
  • Hot Topics
    • What We Want --- SAMHSA Grant Opportunities Due Jan. 22, 2019
    • Anti-Social Personality Disorder >
      • DECONSTRUCTING ANTISOCIAL PERSONALITY DISORDER AND PSYCHOPATHY: A GUIDELINES-BASED APPROACH TO PREJUDICIAL PSYCHIATRIC LABELS [Hofstra Law Review 2013]
      • Personality Disorders -- Unscientific & Vague -- Must Be Reformed
    • Executive Functioning & "Prison Brain" >
      • Job Accommodation Network on Executive Functioning Deficits
    • Medicaid & Medicare Network Adequacy >
      • OIG: STATE STANDARDS FOR ACCESS TO CARE IN MEDICAID MANAGED CARE (Sept. 2014)
      • OIG: ACCESS TO CARE: PROVIDER AVAILABILITY IN MEDICAID MANAGED CARE (Dec. 2014)
      • GAO 15-710: MEDICARE ADVANTAGE: Actions Needed to Enhance CMS Oversight of Provider Network Adequacy (Aug. 2015)
      • CMS: Promoting Access in Medicaid and CHIP Managed Care: A Toolkit for Ensuring Provider Network Adequacy and Service Availability (April 2017)
    • Medicaid Mental Health & Substance Use Disorder Parity >
      • CMS Parity Compliance Toolkit Applying Mental Health and Substance Use Disorder Parity Requirements to Medicaid and Children’s Health Insurance Programs [Jan. 17, 2017]
      • Frequently Asked Questions: Mental Health and Substance Use Disorder Parity Final Rule for Medicaid and CHIP [CMS October 11, 2017]
    • Olmstead Disability Rights >
      • Statement of the Department of Justice on Enforcement of the Integration Mandate of Title II of the Americans with Disabilities Act and Olmstead v. L.C. (2011)
      • Comprehensive Olmstead Planning
      • the Logical Long Term Consequences of our failure to provide Intensive Community MH Treatment
      • Olmstead Nation ---State Pages: How Far to Comply with Olmstead?
  • Take A Walk Around Orchid's Resource Block
  • Colorado Abuse & Neglect Scandals Involving People with Disabilities
  • Mental Health By The Numbers
  • New Science Is Amazing AND It Has HUGE Moral Implications for Our Society: NOW
  • Olmstead & Homelessness
  • Double V
  • " 'Defund the Police" Means 'Invest in the Resources Our Communities Need' " or Don't Cost Shift to the Police
  • VAGUE OLMSTEAD PLANS, EXPENSIVE LITIGATION
  • Updating & Reforming our Understanding & Treatment of "Anti-Social Personality Disorder" Blog
  • Reform of " Anti-Social Personality Disorder" in Criminal Justice
  • CO HB22-1278
  • New Understandings Matter
  • Mental Health, Ethics & Law
  • CO Olmstead Disability Homeless Law & Policy Project
  • Inflammation, the Immune System, Neuro-Developmental Disorders, Psychiatric Disorders, Substance Use Issues & Chronic Disease
  • Microglia and the Brain's Immune System
  • Substance Issues & the Immune System