More Evidence that the Immune System is more complicated than we thought: Alzheimer's and the immune system's Response to "HIERARCHY"

This latest conceptualization of "ALZHEIMER'S" as an AUTOIMMUNE CONDITION is IMPORTANT.

This further develops this idea of COGNITIVE DIFFERENCE/DISABILITY as implicating the IMMUNE SYSTEM --- and the immune system is implicated also with:

• Developmental Differences from Down Syndrome to ADHD & Autism, etc. and
• Psychiatric Disorders
  

Additionally people with DEVELOPMENTAL DIFFERENCES/DISORDERS and PSYCHIATRIC DISORDERS are more at risk for various forms of DEMENTIA.

Further, many people with PSYCHIATRIC DISORDERS do have some form of AUTOIMMUNE DISEASE --- THYROID DISEASE being one of the most common.

Finally, many AUTOIMMUNE DISEASES as well as CANCER have PSYCHIATRIC SYMPTOMS.

So there are MANY MANIFESTATIONS of a "DYSREGULATED" IMMUNE SYSTEM ---- some of those involve:

• MOVEMENT
• PAIN
• COGNITIVE CHALLENGES (this is new), and
• SOCIAL BEHAVIOR (this is new)

We are living in a time of LARGE SCALE ISSUES with CHRONIC DISEASE (including AUTOIMMUNE DISEASE & CANCER), DEVELOPMENTAL DIFFERENCES/DISORDERS, PSYCHIATRIC DISORDERS and DEMENTIA.

People have lived with these challenges and sometimes benefits for a long time:

• But they weren't living as long as we are generally;
• They didn't have the TECHNOLOGY to GO DEEP in their understandings of this the way we do.
  

It has taken widespread low grade inflammation to medium to high inflammation across the globe to expose these common health issues.

BETTER DIET & EXERCISE are essential --- BUT we need to start addressing the challenges of SYSTEMIC DEVELOPMENTAL INFLAMMATION ---

• If we do ----that in itself could help reduce inflammation --- BECAUSE our IMMUNE SYSTEMS as SOCIAL ANIMALS are plugged into the SOCIAL ORDER.*
• We want to take that ETHOS of the MARINES that we're not going to leave anyone behind --- and apply that to PUBLIC HEALTH.
  

Sapolsky on Free Will

I don't agree with everything in the video above --- BUT Sapolsky makes some important points about understanding the BIOLOGY of HUMAN BEHAVIOR ---

• and it's often not exactly what we thought.
  

To me, if we want more FREE WILL or CONTROL--- we need better understandings of our own BIOLOGY.

How Many Angels Can Dance on the Head of a Pin: Getting Beyond the Free Will vs. Determinism Debate

Alzheimer’s Might Not Be Primarily a Brain Disease: A New Theory Suggests It’s an Autoimmune Condition

Sept. 20, 2022

See also:  BBC News:  Low Social Status Can Damage the Immune System

Sir Michael Marmot

BBC Health & Science Reporter James Gallagher quoting Sir Michael Marmot*:

"This is hard science saying there's a plausible biological mechanism that results in clear differences depending where you are in the hierarchy."

Marmot on Pikes Peak

[*I can't resist a crazy non-sequitur SHOUT OUT to the MARMOT VARMITS on Pikes Peak --- I'm sure Sir Michael Marmot would be proud.

Photo Credit US National Park Service]

*I think the stuff on the IMMUNE SYSTEM and the "Social Order" sounds pretty out there but I think the research is substantiating that ----

• Further, one would expect "Social Concerns" for Social Animals to be a BIG Deal.
• But even for Social Animals --- social concerns are not the only thing.
• I think the Greeks and probably a lot of other people were right --- IT IS BALANCE -- but it is so much more COMPLICATED than 4 HUMORS --- and most of this balancing act is going on outside our conscious awareness and is involving trillions of factors that relate to:
  • Our Physical Environment
  • Our Social Environment
  • Our Bodily Environment, and
  • Multiple Systems of the Body

I think one way we've tried to deal with this is have MANY HIERARCHIES.  I think we may be coming to the limit of that as a strategy as we've got almost 8 BILLION people and NONE OF THEM want to be at the BOTTOM of the HIERARCHY or HIERARCHIES.

EQUALITY is really recognizing in the words of Pharrell Williams --- "That we're made of the same things."  ---- No we're NOT clones BUT the more we understand how all this works --- the more choice all of us will have --- Further, this is a LONG TERM PROJECT and to get the BEST RESULTS --- we need to recognize that we're all in this together.