maternal Immune Activation and Mitochondria

Maternal Inflammation During Pregnancy and Offspring Brain Development: The Role of Mitochondria (2022)

In summary, we argue that mitochondrial function is a promising mechanism through which MIA/inflammation during pregnancy can affect the risk for neurodevelopmental and psychiatric disorders.

Elucidating the role of mitochondria as a mediator of MIA-induced alterations in brain development and neurodevelopmental disease risk may not only provide new insight into the pathophysiology of mental health disorders but may also offer new therapeutic targets