| Val's Take
We need a Continuum of Care for "Anti-Social Personality Disorder." |  Article is meant among other things "to enhance societal awareness and reception of the neurobiological basis of antisocial behavior and ASPD [Anti-Social Personality Disorder]." |
| Val's Take/Conjecture
Since then there has been an enormous research focus on Maternal Immune Activation and Developmental Dysregulation of Microglia, the brain's Innate Immune Cells and connecting this to Neuro-Developmental and Psychiatric Disorders. These new understandings are relevant to people with Neuro-Immune Disorders who find themselves homeless and or incarcerated. and dependent on a mental health profession that is relying on an out-of-date diagnostic manual. Further, this isn't just about having the perfect treatment (although we all want that) --- these new understandings themselves are raising reasonable doubt about how we treat people with Neuro-Immune Disorders.  Immunopsychiatry Clinic Further, it is becoming more common to hear Neuro-Developmental and Psychiatric Disorders referred to as NEURO-IMMUNE DISORDERS.   Evidence suggests that altered VN [Vagus Nerve] signaling is linked to changes in the neuroimmune system, including microglia. Dysfunction of microglia, the resident innate immune cells of the brain, is associated with various neurodevelopmental disorders, including schizophrenia, attention deficit hyperactive disorder (ADHD), autism spectrum disorder (ASD), and epilepsy.  Frontiers in Psychiatry Editorial -- March 29, 2019: Recent Advances in Psychiatry From Psycho-Neuro-Immunology Research: Autoimmune Encephalitis, Autoimmune Encephalopathy, and Mild Encephalitis |  Experiences in implementing immunopsychiatry in real life (2023) [focuses primarily on autoimmune diseases with significant psychiatric components]    Immunopsychiatry Meetings We organise bi-monthly online Immunopsychiatry Meetings. This is an exciting new forum bringing together scientists from around the world working at the intersection between psychiatry and immunology. The meetings alternate talks between world's leading scientists and early career scientists working in the field of immunopsychiatry. The meetings are supported by the European College of Neuropsychopharmacology (ECNP) Immuno-NeuroPsychiatry Network. Our aim is to provide the opportunity for researchers interested in immunopsychiatry to come together and to share their research, exchange ideas, and engage in networking. The meetings are free and open to any scientist!   |
| Val's Take/Conjecture
Further, we are prepared to fund Alzheimer's Units and Locked Nursing Home Wards
 So What? "These findings suggest major changes in microglial subsets developmental trajectories and reactivity contributing to NDDs [Neuro-Developmental Disorders] induced by neonatal inflammation." Staffing
| For younger people with Neuro-Developmental Disorders and an IQ over 70
 "These findings provide novel, prospective evidence that maternal inflammation uniquely predicts child cognitive flexibility deficits, and that these associations depend on the timing of exposure before or during pregnancy."  The effects of Maternal Immune Activation are not static over the life span, although those effects are not uniform and are idiosyncratic.
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| Val's Take/Conjecture
There are some Neuro-Diverse folks often viewed as having "ADHD" --- who need a lot of physical activity --
 For some people, just saying MORE EXERCISE is the Answer is going to lead to DISASTER.
|  For kids who need significantly more physical activity at school, "fidget spinners" and "brain breaks" may be far from adequate educational responses. Further kids in general, especially neuro-diverse kids need individualized programming and attention. THAT MEANS ADEQUATE STAFFING which many Colorado schools do not have.  Increased physical activity can spur cognitive development, help children manage symptoms of ADHD (2024) “I’m really interested in looking at what a typical day looks like for a child with ADHD, and the typical activity levels,” Logan said. “There’s hyperactivity and inattention. So we might see differences in activity levels depending on which symptom is greater in a child. Hyperactivity-based children are very active. "Maybe those children need more bouts of physical activity throughout the day to really burn off some energy and to refocus when they come back in for the school day. "That goes in line with where physical activity guidelines are going… more physical activity spread throughout the day might be more beneficial for us.”  Val's Conjecture I think the benefits of exercise and the frequency and intensity of exercise vary greatly among individuals generally, and among Neuro-Diverse people with MITOCHONDRIAL DYSFUNCTION. |
| Val's Take/Conjecture
On the other hand, kids with Medium Needs and "ADHD" and/or "Autism" are challenging staffing schedules.
A legislative audit of School Staffing for kids with disabilities could provide the data that is needed.
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| Val's Take
|  Lois Curtis, one of the original Olmstead plaintiffs "HB25-1017 - lays the groundwork for putting Olmstead into state statute should the Supreme Court of the United States overturn the decision." |
 Schizophrenia: more same than different to neurodevelopmental disorders?"The neurodevelopmental continuum is based on emerging evidence for shared genetic risk and overlapping pathogenic mechanisms of neurodevelopmental disorders in early ages – Intellectual disability, autism spectrum disorder, attention-deficit/hyperactivity disorder (ADHD) – with schizophrenia and bipolar disorder." [Va]'s Take: Many researchers are including aspects of Depression in that NEURO-DEVELOPMENTAL CONTINUUM]. |
| Val's Take/Conjecture Many illnesses and disabilities have some element of FATIGUE. People with Chronic Fatigue Syndrome or Myalgic Encephalomyelitis had a hard time getting this neurological disorder taken seriously. Fatigue is also a feature of many Neuro-Developmental & Psychiatric Disorders. In the case of Neuro-Developmental and Psychiatric Disorders, the issue of fatigue is often flying under the radar for patients. In part, I think that leads to the underlying biology becoming even more dysregulated and presenting more serious symptoms. Further, the need to manage the Fatigue is often met with an even greater resolve to WORK THROUGH IT -- which can further exacerbate the Energy Issues for a Brain that already has energy issues.  As our understanding of the biology of Neuro-Developmental and Psychiatric Disorders is making dramatic improvements --- fatigue will be more treated and accommodated. | Recently, "BRAIN ENERGY" has become a Hot Topic in Mental Health. Dr. Chris Palmer and others are pushing a KETO diet and there has been some promising research.   "The accumulation of defective mitochondria accelerates cellular nerve dysfunction. "In addition, impaired mitochondria aggravate alterations in the brain microenvironment, promoting neuroinflammation and energy depletion, thereby exacerbating the development of depression."   |
| Val's Take
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| Val's Take/Conjecture
|  HUD Takes Action to Support Community Living for People with Disabilities (August 2024) After 25 years of Olmstead, it became painfully obvious that there were not enough housing resources for people with disabilities in most states, and it wasn't getting addressed ---- except maybe by Denver Mayor Mike Johnston and he was relying at least in great part on Federal Housing Vouchers. Could a 2nd Trump Administration roll back "Olmstead Housing Vouchers" --- It could but it may not want to. If HUD can cover Housing Vouchers, I think that makes the process of "Olmstead Planning" much easier for all the Stakeholders. I don't think a 2nd Trump Administration is going to be focused on Olmstead Enforcement --- but there could be encouragement of reasonable, flexible plans to address the needs of people of disabilities who are institutionalized or at risk of institutionalization. |